Blackstone Labs is back at it again. This time, we’re tearing down the walls of stubborn fat reserves and raiding BMI indexes with our new secret weapon: Trojan Horse.
We all know the conventional approach to burning fat: load up on caffeine or other hard-hitting stimulants until your central nervous system is completely taxed, and then you crash hard. While a lot of people are totally okay with this, we recognize that there are others who are not a fan of feeling like their heart is going to pop out of their chest, and of course, the bane of the working person, insomnia.
Luckily for you, the brilliant mind of our Chief Science Officer, The Guerrilla Chemist has discovered a way to burn reserves of fat without any kind of stimulants. Yes, you’ve read correctly, Trojan Horse is completely stimulant free. You can take it minutes before bed and rest well, knowing that you’ll be burning fat all through the night.
Trojan Horse utilizes a cellular process known as uncoupling, one of the most powerful ways your body can burn fat. Uncoupling essentially causes your body to use much more energy than it normally would to create ATP, and this extra energy comes from the breakdown of fat. Previously, the most powerful (and harmful) fat burner of all time, 2,4-Dinitrophenol (otherwise known as DNP), used uncoupling to burn fat. Unfortunately, DNP, a former substitute for TNT and dynamite, is very toxic and produces tons of cell-damaging free radicals and organ failure. While Trojan Horse is an uncoupler and does cause your body to breakdown fat for energy, we are proud to state that Trojan Horse is NOT TOXIC IN ANY CAPACITY WHATSOEVER.
Much like how the Achaeans used clever tactics to burn Troy to the ground, Trojan Horse uses uncoupling to trick your body into using much more energy than it actually needs for the production of ATP. This excess workload forces your body burn its reserves of fat to the ground.
Take up arms and fight the good fight against fat. Burn it to the ground with the newest addition to your arsenal: Trojan Horse!
The Science Behind Trojan HorseThe mechanism by which Trojan Horse works is multi-faceted. The first part of the mechanism involves the combination of hydroxycitrate (HCA) and L-carnitine. These two molecules synergistically work together to enhance the activity of the enzyme carnitine palmitoyltransferase I (CPT), the rate limiting enzymatic step for transporting fatty acids into the mitochondria for beta oxidation (fat burning). HCA inhibits the production of malonyl CoA, an allosteric inhibitor of CPT. Carnitine is an essential cofactor for CPT activity and enhances ketogenesis.
During ketogenesis, more ADP is generated, which results in an increased electrochemical proton gradient for ATP synthase.
ATP synthase is responsible for the production of ATP and requires a high electrochemical gradient to work sufficiently.
Pyruvate is the end product of glycolysis, the breakdown of carbohydrates for energy. Pyruvate converts into acetyl CoA that enters the Krebs cycle, which generates the electron carriers NADH and FADH2. The molecules are necessary for the Electron Transport Chain (ETC), where your body produces ATP. Essentially, pyruvate converts into oxaloacetate in the body, which has high redox potential.
This is energetically favorable, so most of the oxaloacetate will be reduced to malate, which already exists in large quantities in the mitochondria. Pyruvate can be expected to catalyze the transfer of high-energy electrons from mitochondria to the cytosol. The resulting decrease in mitochondrial NADH should stimulate the Krebs cycle and promote reverse electron transport.
Reverse Electron transport is a process by which electrons are shuttled away from the ETC and into the cytosol, where they can re-enter the respiratory chain at the CoQ level. This process significantly disrupts the electrochemical proton gradient needed to generate ATP, effectively “uncoupling” the Krebs cycle and ETC. As a result, more energy is utilized in the process of making ATP, and the complete oxidation of fatty acids to CO2 is increased in an effort to get the necessary electrons needed to repair the electrochemical gradient.
Figure 1: Electron Chain Transport
Figure 1 shows the flow of electrons from glycolysis to the Krebs cycle, to the ECT.
Notice the proton gradient denoted by a “+” in the intermembrane space, and a “-“ in
the cytoplasm. This is the electrochemical gradient that is disrupted by the active
ingredients in Trojan Horse, which causes your body to oxidize more fat in an
attempt to recreate this electrochemical potential.